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Process R&D
Delivering high quality synthetic processes
- Scale up of candidates for pre-clinical studies
- Synthetic route scouting and screening of reaction conditions
- Process development and optimisation from grams to metric ton
- Impurity characterisation and synthesis
- Technology transfer to manufacturing
- Full range of analytical equipment/techniques (TGA, DSC, Karl-Fischer etc.)
- The process chemists work closely with both medicinal chemistry teams, as well as, the manufacturing plant chemists at different points of development to ensure smooth progress
- Communication is key as it is often necessary to balance the varying needs of delivering material for key studies with gaining a complete understanding of complex chemistry
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